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Ros1 is highly homologous with alk, and can also regulate normal physiological activities of cells

The overexpression of both is closely related to the development and metastasis of tumors Although their frequency is relatively low, their detection is important for patient care and guides therapeutic decisions The accepted methods used for th … Introduction anaplastic lymphoma kinase (alk) is a tyrosine kinase that can be aberrantly expressed in several tumor types The most common alk rearrangement in nsclc juxtaposes the 5' end of the echinoderm microtubule. Similarly to alk nsclc, patients with ros1+ nsclc tend to have minimal smoking history and be of the female sex.

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